Mise en place. Measure and prepare all ingredients. Preheat the oven to 350 degrees Fahrenheit. Line a 1 pound (8.5 x 4.5 x 2.75 inch) loaf pan with parchment paper. Measure and prepare all ingredients.
Prepare the dry ingredients. In a medium bowl, whisk together the flour, baking powder, and salt.
Mix the wet ingredients. In a small bowl, whisk together the blended cottage cheese, milk, lemon zest, lemon juice, and vanilla extract. I typically do this in a 2 cup glass measuring cup for easy pouring later.
Cream the butter and sugar. In a large bowl or stand mixer fitted with the paddle attachment, cream the butter and sugar until very light and fluffy (4-6 minutes). This helps give the loaf cake its fluffy texture.
Add the eggs. Beat in the eggs one at a time. Scrape down the sides and bottom of the bowl, and mix again to incorporate.
Combine the dry and wet ingredients. Alternate adding the dry ingredients and wet mixture to the butter/sugar/egg mixture. With the mixer running on low, start with ⅓ of the dry mix and stir gently. Add ½ the wet mixture and stir gently. Repeat, ending with the dry mix until it's just incorporated.Scrape down the bowl to ensure everything is incorporated, being careful not to overmix. The batter will be thick. Bake. Pour the batter into the prepared loaf pan, and smooth the top with a spatula. Bake for 50-60 minutes, or until a toothpick inserted in the center comes out clean.
Cool. Let the loaf cake cool in the pan for 10 minutes, then transfer the loaf to a wire rack to cool completely before adding the glaze.